Objective To investigate the relationship among left atrial structure indexes, left atrial appendage
spontaneous echo contrast (LAASEC) and left atrial appendage thrombus (LAAT) in patients with non-valvular atrial
fibrillation (NVAF). Methods NVAF patients were chosen from Department of Cardiology in the First Affiliated
Hospital of Xi`an Jiaotong University from Mar. 1, 2016 to Dec. 31, 2019. All patients were divided, according to
the status of left atrial appendage (LAA) shown by transesophageal echocardiography (TEE), into thrombus group
(n=42), spontaneous echo contrast group (SEC group, n=69) and control group (no LAASEC or no LAAT, n=273).
The left atrial structure indexes, and correlation among them and LAASEC and LAAT were analyzed. Results
LAA open caliber (OR=1.208, 95%CI: 1.094~1.333, P<0.001), LAA flow velocity<40 cm/s (OR=72.329, 95%CI:
24.065~217.392, P<0.001), left atrial mediolateral diameter (OR=1.037, 95%CI: 1.010~1.065, P=0.008), left atrial
suproinferior diameter (OR=1.071, 95%CI: 1.029~1.116, P=0.001), the interval between right superior pulmonary
vein (RSPV) and right inferior pulmonary vein (RIPV, OR=1.089, 95%CI: 1.019~1.163, P=0.012), and interval
between RSPV and left superior pulmonary vein (LSPV, OR=1.034, 95%CI: 1.004~1.066, P=0.027) all were
independent risk factors of LAASEC. LAA flow velocity<40 cm/s (OR=15.268, 95%CI: 6.652~35.045, P<0.001)
was an independent risk factor of LAAT. Conclusion In clinical practice, more attention should be paid to NVAF
patients with the above risk factors, and early intervene will reduce stroke incidence.